Article
Heterogeneity of the antigenic site responsible for the induction of neutralizing antibodies in infectious bursal disease virus.
Archives of virology - 1 Jan 1991
Oppling V, Müller H, Becht H
Abstract excerpt
Using neutralizing monoclonal antibodies, three categories of escape mutants were selected from a stock of wild-type infectious bursal disease virus (IBDV). Additional mutants were found, where alterations coexisted in two or three of these epitopes. Although each group of mutants had a distinct...
Topics
- Animals
- Antibodies, Monoclonal
- Antibodies, Viral
- Antigenic Variation
- Antigens, Viral
- Cell Line
- Chickens
- Epitopes
- Immunoblotting
- Infectious bursal disease virus
- Mutation
- Neutralization Tests
- Precipitin Tests
- Rabbits