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Article

Structural and functional analysis of pp70S6k.

Proceedings of the National Academy of Sciences of the United States of America - 5 Dec 1995

Cheatham L, Monfar M, Chou M M, Blenis J

Abstract excerpt

The pp70/85-kDa S6 kinases, collectively referred to as pp70S6k, are thought to participate in transit through the G1 phase of the cell cycle. pp70S6k regulates the phosphorylation of the 40S ribosomal protein S6 and the transcription factor CREM tau. pp70S6k is regulated by serine/threonine phos...

Topics

Androstadienes
Animals
Cells, Cultured
Cricetinae
DNA Mutational Analysis
Drug Resistance
Gene Expression Regulation, Enzymologic
Immunosuppressive Agents
Mutation
Phosphorylation
Polyenes
Protein Serine-Threonine Kinases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Ribosomal Protein S6 Kinases

Sequence Deletion

Sirolimus

Wortmannin

Source

Open in PubMed Open full text

Identifiers

PMID: 8524831
DOI: 10.1073/pnas.92.25.11696
PMCID: PMC40469

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8524831-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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