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The Multifaceted Role of S6K1 in Cellular Regulation: Structural Insights, Isoform-Specific Functions, and Therapeutic Potential

2024-08-15

Abstract excerpt

S6K1 (ribosomal protein S6 kinase beta-1) is a critical serine/threonine kinase involved in the regulation of various cellular processes, including protein synthesis, gene expression, and metabolic homeostasis. The structural complexity of S6K1, with its multiple isoforms and unique kinase domain, allows for diverse functionality across different cellular contexts. In this review, we report the intricate structure...

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Literature Corpus work
414a0e18-0b39-55b8-a373-53b697ce3f4a
DOI
10.20944/preprints202408.1156.v1
Open publication

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