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Article

Exploiting p70 S6 kinase as a target for ovarian cancer

7 May 2012

Abstract excerpt

INTRODUCTION: The p70 S6 kinase (p70(S6K)) is frequently active in ovarian and a wide range of cancer types, and it has a crucial role in several processes considered hallmarks of cancer. Therefore, blocking p70(S6K) expression or activity may present a promising strategy for anticancer treatment. AREAS COVERED: The current understanding of the molecular mechanisms that govern p70(S6K) regulation as well as its...

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PMID: 22564017
DOI: 10.1517/14728222.2012.684680

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