Article
Yeast MEK-dependent signal transduction: response thresholds and parameters affecting fidelity.
Molecular and cellular biology - 1 Dec 1995
Yashar B, Irie K, Printen J A, Stevenson B J, Sprague G F, Matsumoto K, Errede B
Abstract excerpt
Ste7p and Mkk1p are MEK (MAPK/ERK kinase) family members that function in the mating and cell integrity signal transduction pathways in Saccharomyces cerevisiae. We selected STE7 and MKK1 mutations that stimulated their respective pathways in the absence of an inductive signal. Strikingly, serine...
Topics
- Alleles
- Amino Acid Sequence
- Crosses, Genetic
- Genes, Fungal
- Genetic Variation
- Genotype
- Histidine
- MAP Kinase Kinase 1
- Mitogen-Activated Protein Kinase Kinases
- Molecular Sequence Data
- Mutagenesis, Site-Directed
- Protein Kinases
- Protein Serine-Threonine Kinases
- Protein-Tyrosine Kinases