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Article

Yeast MEK-dependent signal transduction: response thresholds and parameters affecting fidelity.

Molecular and cellular biology - 1 Dec 1995

Yashar B, Irie K, Printen J A, Stevenson B J, Sprague G F, Matsumoto K, Errede B

Abstract excerpt

Ste7p and Mkk1p are MEK (MAPK/ERK kinase) family members that function in the mating and cell integrity signal transduction pathways in Saccharomyces cerevisiae. We selected STE7 and MKK1 mutations that stimulated their respective pathways in the absence of an inductive signal. Strikingly, serine-to-proline substitutions at analogous positions in Ste7p (position 368) and Mkk1p (position 386) were recovered by...

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Identifiers

PMID: 8524219
DOI: 10.1128/MCB.15.12.6545
PMCID: PMC230907

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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