Article
A subset of FG-nucleoporins is necessary for efficient Msn5-mediated nuclear protein export.
Biochimica et biophysica acta - 1 May 2013
Finn Erin M, DeRoo Elise P, Clement George W, Rao Sheila, Kruse Sarah E, Kokanovich Kate M, Belanger Kenneth D
Abstract excerpt
The transport of proteins between the cytoplasm and nucleus requires interactions between soluble transport receptors (karyopherins) and phenylalanine-glycine (FG) repeat domains on nuclear pore complex proteins (nucleoporins). However, the role of specific FG repeat-containing nucleoporins in nuclear protein export has not been carefully investigated. We have developed a novel kinetic assay to investigate the...
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