Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

hemipterous encodes a novel Drosophila MAP kinase kinase, required for epithelial cell sheet movement.

Cell - 3 Nov 1995

Glise B, Bourbon H, Noselli S

Abstract excerpt

During Drosophila embryogenesis, a cell sheet movement, dorsal closure, allows establishment of the dorsal epidermis. In this morphogenetic process, lateral epithelia undergo a dramatic movement toward the dorsal midline. In the mutant hemipterous (hep), spreading of the epithelia is blocked; in genetically sensitized hep embryos, cell sheet movement can be arrested at any time, indicating hep requirement in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amino Acid Sequence
Share to Base Sequence
Share to Cloning, Molecular

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Drosophila

Share to Drosophila Proteins

Share to Gene Expression

Share to Molecular Sequence Data

Share to Mutation

Source

Identifiers

PMID: 8521475
DOI: 10.1016/0092-8674(95)90123-x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

hemipterous encodes a novel Drosophila MAP kinase kinase, required for epithelial cell sheet movement.PMID 8521475Read ↗

The Drosophila JNK pathway controls the morphogenesis of imaginal discs during metamorphosis.Semantic proximity Read ↗

The Drosophila Ste20-related kinase misshapen is required for embryonic dorsal closure and acts through a JNK MAPK module on an evolutionarily conserved signaling pathway.Semantic proximity Read ↗

JNK signaling pathway is required for efficient wound healing in Drosophila.Semantic proximity Read ↗

Downregulation of Jun kinase signaling in the amnioserosa is essential for dorsal closure of the Drosophila embryo.Semantic proximity Read ↗

dPak is required for integrity of the leading edge cytoskeleton during Drosophila dorsal closure but does not signal through the JNK cascade.Semantic proximity Read ↗

Defective dorsal closure and loss of epidermal decapentaplegic expression in Drosophila fos mutants.Semantic proximity Read ↗

Thorax closure in Drosophila: involvement of Fos and the JNK pathway.Semantic proximity Read ↗

Activation of the JNK pathway during dorsal closure in Drosophila requires the mixed lineage kinase, slipper.Semantic proximity Read ↗

Epithelial sheet movement requires the cooperation of c-Jun and MAP3K1.Semantic proximity Read ↗

Signalling crosstalk at the leading edge controls tissue closure dynamics in the Drosophila embryo.Semantic proximity Read ↗

Dpp signalling orchestrates dorsal closure by regulating cell shape changes both in the amnioserosa and in the epidermis.Semantic proximity Read ↗

Cellular and genetic analysis of wound healing in Drosophila larvae.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.