Article
Major histocompatibility complex gene mapping in the amphibian Xenopus implies a primordial organization.
Proceedings of the National Academy of Sciences of the United States of America - 27 May 1997
Nonaka M, Namikawa C, Kato Y, Sasaki M, Salter-Cid L, Flajnik M F
Abstract excerpt
One of the most provocative recent discoveries in immunology was the description of a genetic linkage in the major histocompatibility complex (MHC) between structurally unrelated genes whose products are involved in processing and presentation of antigens for recognition by T lymphocytes. Genes encoding MHC class I molecules, which bind and present at the cell surface proteolytic fragments of cytosolic proteins,...
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