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The MHC class I genes of the rhesus monkey. Different evolutionary histories of MHC class I and II genes in primates

1 Jun 1996

Abstract excerpt

Homologues of the human HLA-A and -B MHC class I loci have been found in great apes and Old World primates suggesting that these two loci have existed for at least 30 million years. The C locus, however, shows some sequence similarity to the B locus and has been found only in gorillas, chimpanzees, and humans. To determine the age of the MHC class I C locus and to examine the evolution of the A and B loci we have...

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PMID: 8648109
DOI: 10.4049/jimmunol.156.12.4656

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