Article
A human gene homologous to the formin gene residing at the murine limb deformity locus: chromosomal location and RFLPs.
American journal of human genetics - 1 Apr 1991
Maas R L, Jepeal L I, Elfering S L, Holcombe R F, Morton C C, Eddy R L, Byers M G, Shows T B, Leder P
Abstract excerpt
The murine limb deformity (ld) locus resides on mouse chromosome 2 and gives rise to a recessively inherited, characteristic limb deformity/renal aplasia phenotype. In this locus in the mouse, a gene, termed the "formin" gene, has been identified which encodes an array of differentially processed...
Topics
- Alleles
- Animals
- Chromosomes, Human, Pair 15
- Exons
- Female
- Gene Frequency
- Humans
- Hybrid Cells
- Limb Deformities, Congenital
- Male
- Mice
- Molecular Sequence Data
- Mutation
- Pedigree
- Polymorphism, Restriction Fragment Length