Article
A human gene homologous to the formin gene residing at the murine limb deformity locus: chromosomal location and RFLPs.
American journal of human genetics - 1 Apr 1991
Maas R L, Jepeal L I, Elfering S L, Holcombe R F, Morton C C, Eddy R L, Byers M G, Shows T B, Leder P
Abstract excerpt
The murine limb deformity (ld) locus resides on mouse chromosome 2 and gives rise to a recessively inherited, characteristic limb deformity/renal aplasia phenotype. In this locus in the mouse, a gene, termed the "formin" gene, has been identified which encodes an array of differentially processed transcripts in both adult and embryonic tissues. A set of these transcripts are disrupted in independent mutant mouse...
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