Article
Selective breeding for alcohol withdrawal severity.
Behavior genetics - 1 Mar 1993
Crabbe J C, Phillips T J
Abstract excerpt
Mouse lines have been genetically selected to be alcohol Withdrawal Seizure Prone (WSP) or Resistant (WSR). The selection index is the severity of withdrawal handling-induced convulsions seen after removal of mice from chronic exposure to ethanol vapor. Behavioral, pharmacological, and neurochemi...
Topics
- Alcohol Withdrawal Delirium
- Alcoholism
- Animals
- Brain
- Mice
- Mice, Inbred Strains
- Models, Genetic
- Phenotype
- Selection, Genetic
