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Article

Polygenic and single-gene determination of responses to ethanol in BXD/Ty recombinant inbred mouse strains.

Neurobehavioral toxicology and teratology - 1 Jan 2000

Crabbe J C, Kosobud A, Young E R, Janowsky J S

Abstract excerpt

Male mice of parent inbred strains C57BL/6J and DBA/2J, and mice from several of the BXD/Ty Recombinant Inbred (RI) strains derived from the cross of the parent inbred strains were tested for responsiveness to ethanol. Separate groups of mice from these strains were characterized for sensitivity to ethanol's effects to increase activity in an open field and to induce ambulatory ataxia in the grid test. The strain...

Topics

Alcohol Drinking
Alcohol Withdrawal Delirium
Alcoholism
Animals
Behavior, Animal
Ethanol
Genotype
Humans
Male
Mice
Mice, Inbred Strains
Motor Activity

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Motor Skills

Postural Balance

Recombination, Genetic

Seizures

Source

Identifiers

PMID: 6683363

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-6683363-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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