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Article

An insertion-deletion event in murine immunoglobulin kappa gene resembles mutations at heavy-chain disease loci.

Somatic cell and molecular genetics - 1 Mar 1993

Chou C L, Morrison S L

Abstract excerpt

The analysis of spontaneous somatic mutants gives insights into the regulation of gene expression. Human heavy-chain disease (HCD) is a monoclonal lymphoproliferative disorder characterized by the presence of truncated immunoglobulin (Ig) heavy chains without associated light chains. To better understand the molecular mechanisms leading to the loss of light-chain production, we have examined a murine cell line...

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PMID: 8511672
DOI: 10.1007/BF01233529

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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