Article
Functional characterization of the M-type K15-encoded membrane protein of Kaposi's sarcoma-associated herpesvirus.
The Journal of general virology - 1 Jun 2007
Wang Linding, Brinkmann Melanie M, Pietrek Marcel, Ottinger Matthias, Dittrich-Breiholz Oliver, Kracht Michael, Schulz Thomas F
Abstract excerpt
Kaposi's sarcoma-associated herpesvirus (KSHV) or human herpesvirus 8 is the causative agent of Kaposi's sarcoma, primary effusion lymphoma and the plasma-cell variant of multicentric Castleman's disease. Its alternatively spliced K15 gene encodes several membrane proteins with varying numbers of transmembrane domains. Two highly diverged alleles of the K15 gene, termed predominant (P) and minor (M), exist and...
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