Article
Function of ammonium transporter A in the initiation of culmination of development in Dictyostelium discoideum.
Eukaryotic cell - 1 Jul 2006
Singleton Charles K, Kirsten Janet H, Dinsmore Colin J
Abstract excerpt
The histidine kinase DhkC controls a phosphorelay involved in regulating the slug versus culmination choice during the multicellular developmental program of Dictyostelium discoideum. When the relay is active, slug migration is favored due to the activation of a cyclic AMP (cAMP) phosphodiesterase and the resultant lowering of the intracellular and extracellular levels of cAMP. Ammonia signaling represents one...
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