Article
Possible mechanism for the TCR beta-chain associated EAE resistance of LER rats.
Journal of neuroscience research - 15 Sept 1996
Bourque M M, Martin A M, Desquennes-Clark L, Heber-Katz E, Blankenhorn E P
Abstract excerpt
LER rats are resistant to the active induction of experimental allergic encephalomyelitis (EAE). The mechanism of their resistance to EAE has yet to be defined, although LER rats are susceptible to adoptively transferred EAE. Genetic analysis of LER and the susceptible LEW rat suggests that a gene linked to the T cell receptor (TCR) beta-chain complex contributes to EAE resistance. This result is consistent with...
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