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Article

An influenza virus temperature-sensitive mutant defective in the nuclear-cytoplasmic transport of the negative-sense viral RNAs.

Virology - 1 Jun 1993

Enami K, Qiao Y, Fukuda R, Enami M

Abstract excerpt

An influenza A virus mutant ts-51, which contains a temperature-sensitive (ts) defect in the genome encoding the M1 and M2 proteins, was characterized. Nucleotide sequencing of the M segment revealed a predicted single amino acid change of phenylalanine to serine at amino acid position 79 in the M1 protein. The nuclear-cytoplasmic transport of the negative-sense viral RNAs (vRNAs) was then investigated using an...

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Identifiers

PMID: 8503186
DOI: 10.1006/viro.1993.1324

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