Article
Hyperphosphorylation of mutant influenza virus matrix protein, M1, causes its retention in the nucleus.
Journal of virology - 1 Jan 1995
Whittaker G, Kemler I, Helenius A
Abstract excerpt
The matrix (M1) protein of influenza virus is a major structural component, involved in regulation of viral ribonucleoprotein transport into and out of the nucleus. Early in infection, M1 is distributed in the nucleus, whereas later, it is localized predominantly in the cytoplasm. Using immunofluorescence microscopy and the influenza virus mutant ts51, we found that at the nonpermissive temperature M1 was...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
