Article
HLA-DR beta chain residue 86 controls DR alpha beta dimer stability.
European journal of immunology - 1 Jun 1993
Verreck F A, Termijtelen A, Koning F
Abstract excerpt
Major histocompatibility complex class II molecules exist in two forms, which can be distinguished on the basis of their stability in sodium dodecyl sulfate (SDS) as SDS-stable and SDS-unstable alpha beta dimers. The ratio of stable vs. unstable alpha beta dimers varies between murine H-2 alleles and isotypes, but the molecular basis for this observation is unknown. Here we show that for the human HLA-DRB1 and...
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