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Article

Disulfide bond-mediated dimerization of HLA-G on the cell surface

26 Nov 2002

Abstract excerpt

HLA-G is a nonclassical class I MHC molecule with an unknown function and with unusual characteristics that distinguish it from other class I MHC molecules. Here, we demonstrate that HLA-G forms disulfide-linked dimers that are present on the cell surface. Immunoprecipitation of HLA-G from surface biotinylated transfectants using the anti-beta2-microglobulin mAb BBM.1 revealed the presence of an approximately...

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PMID: 12454284
DOI: 10.1073/pnas.212643199

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