Article
Identification of a recombinogenic major histocompatibility complex Q gene with diverse alleles.
The Journal of experimental medicine - 1 Jun 1993
Cullen M K, Lapierre L A, Kesari K V, Geliebter J
Abstract excerpt
Structural diversity enables class Ia molecules to present a diverse repertoire of peptides to the T cell receptor. This diversity is thought to be generated by recombinations between class I genes. We have found that two class Ib Q2 alleles exhibit extremely high sequence diversity, even higher...
Topics
- Alleles
- Amino Acid Sequence
- Animals
- Base Sequence
- Genes, MHC Class I
- H-2 Antigens
- Histocompatibility Antigens Class I
- Mice
- Molecular Sequence Data
- Oligodeoxyribonucleotides
- Recombination, Genetic
- Selection, Genetic
- Transcription, Genetic