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Article

Identification of a recombinogenic major histocompatibility complex Q gene with diverse alleles.

The Journal of experimental medicine - 1 Jun 1993

Cullen M K, Lapierre L A, Kesari K V, Geliebter J

Abstract excerpt

Structural diversity enables class Ia molecules to present a diverse repertoire of peptides to the T cell receptor. This diversity is thought to be generated by recombinations between class I genes. We have found that two class Ib Q2 alleles exhibit extremely high sequence diversity, even higher than class Ia alleles. Clustered nucleotide differences between Q2b and Q2k suggest that this sequence diversity was...

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Identifiers

PMID: 8496692
DOI: 10.1084/jem.177.6.1803
PMCID: PMC2191030

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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