Article
Molecular organization of the D-Qa region of t-haplotypes suggests that recombination is an important mechanism for generating genetic diversity of the major histocompatibility complex.
Mammalian genome : official journal of the International Mammalian Genome Society - 1 Jan 1991
Uehara H, Abe K, Flaherty L, Bennett D, Artzt K
Abstract excerpt
We have determined the molecular maps of the H-2D and Qa regions of the t-complex haplotypes t12 and tw5 by chromosomal walking. Analysis with class I probes and other probes unique to the H-2D:Qa subregion indicates that the class I gene organization of t12 is: D1-D2-Q1-Q2-Q3-Qx-Q4-Q5-Q10, while...
Topics
- Animals
- Chromosome Mapping
- DNA Transposable Elements
- Genetic Variation
- H-2 Antigens
- Haplotypes
- Histocompatibility Antigen H-2D
- Histocompatibility Antigens Class I
- Mice
- Mice, Inbred C3H
- Polymorphism, Restriction Fragment Length
- Recombination, Genetic