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Article

Polymorphisms in pockets of major histocompatibility complex class I molecules influence peptide preference.

The Journal of experimental medicine - 1 Jun 1993

Rohren E M, Pease L R, Ploegh H L, Schumacher T N

Abstract excerpt

The set of peptides that is bound by a given major histocompatibility complex class I product can be described by one or two properly spaced anchor residues, and two properly spaced peptide termini, approximately 8-10 residues apart. Using radiolabeled peptide libraries, we examined whether mutations in those "pockets" in class I Kb molecules that do not seem critically involved in the interaction with the...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 8496687
DOI: 10.1084/jem.177.6.1713
PMCID: PMC2191031

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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