Article
Role of palmitoylation on the neuronal glycine transporter GlyT2.
Journal of neurochemistry - 1 Sept 2024
Felipe R, Sarmiento-Jiménez J, Camafeita E, Vázquez J, López-Corcuera B
Abstract excerpt
The neuronal glycine transporter GlyT2 removes glycine from the synaptic cleft through active Na+, Cl-, and glycine cotransport contributing to the termination of the glycinergic signal as well as supplying substrate to the presynaptic terminal for the maintenance of the neurotransmitter content in synaptic vesicles. Patients with mutations in the human GlyT2 gene (SLC6A5), develop hyperekplexia or startle...
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