Article
Molecular analysis of human beta-arrestin-1: cloning, tissue distribution, and regulation of expression. Identification of two isoforms generated by alternative splicing.
The Journal of biological chemistry - 5 May 1993
Parruti G, Peracchia F, Sallese M, Ambrosini G, Masini M, Rotilio D, De Blasi A
Abstract excerpt
The cDNA for human beta-arrestin-1 was cloned by polymerase chain reaction (PCR) and identified based on its remarkably high amino acid identity (98.6%) with the bovine sequence. Two alternatively spliced isoforms of human beta-arrestin-1, differing only in the presence or absence of 24 base pair...
Topics
- Alternative Splicing
- Amino Acid Sequence
- Animals
- Antigens
- Arrestins
- Base Sequence
- Blotting, Southern
- Cattle
- Cells, Cultured
- Cholera Toxin
- Cloning, Molecular
- Colforsin
- DNA
- Endothelium, Vascular
- Eye Proteins
- Gene Expression Regulation
- Genetic Variation
- Humans