Phenotypic and functional characterization of competitive long-term repopulating hematopoietic stem cells enriched from 5-fluorouracil-treated murine marrow.

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Article

Phenotypic and functional characterization of competitive long-term repopulating hematopoietic stem cells enriched from 5-fluorouracil-treated murine marrow.

Blood - 1 May 1993

Szilvassy S J, Cory S

Abstract excerpt

Lymphomyeloid stem cells from the bone marrow of C57BL/6 mice treated with 5-fluorouracil (5-FU) were characterized with respect to 12 parameters using fluorescence-activated cell sorting and a competitive long-term repopulation assay. Stem cells were larger than lymphocytes and exhibited side li...

Topics

Animals
Antigens, Surface
Bone Marrow
Bone Marrow Cells
CD4 Antigens
Cells, Cultured
Colony-Forming Units Assay
Female
Fluorouracil
Hematopoietic Stem Cells
Leukocyte Common Antigens
Male
Mice
Mice, Inbred C57BL
Phenotype

Source

Open in PubMed

Identifiers

PMID: 8481511

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8481511-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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