Article
A neuropeptide Y locus on chromosome 4 cosegregates with blood pressure in the spontaneously hypertensive rat.
Biochemical and biophysical research communications - 15 Apr 1993
Katsuya T, Higaki J, Zhao Y, Miki T, Mikami H, Serikawa T, Ogihara T
Abstract excerpt
Recent advances in molecular biology have allowed the study of the candidate genes for essential hypertension. To identify the genes responsible for basal blood pressure in the spontaneously hypertensive rat strain, the rat model of genetic hypertension, we performed a cosegregation analysis between the genotype and blood pressure in a set of male F2 progeny obtained from SHR and Wistar-Kyoto rats, a reference...
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