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Article

Cosegregation analysis of natriuretic peptide genes and blood pressure in the spontaneously hypertensive rat.

Clinical and experimental pharmacology & physiology - 1 Dec 2003

Ye Ping, West Malcolm J

Abstract excerpt

1. The natriuretic peptide precursor A (Nppa) and B (Nppb) genes are candidate genes for hypertension and cardiac hypertrophy in the spontaneously hypertensive rat (SHR). The purpose of the present study was to determine the role of the Nppa and Nppb genes in the development of hypertension in the SHR. 2. A cohort (n = 162) of F2 segregating intercross animals was established between strains of hypertensive SHR...

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Source

Identifiers

PMID: 14678232
DOI: 10.1111/j.1440-1681.2003.03937.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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