Alteration of cardiac collagen phenotypes in hypertensive hypertrophy: role of blood pressure.

doi:10.1006/jmcc.1993.1021

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Article

Alteration of cardiac collagen phenotypes in hypertensive hypertrophy: role of blood pressure.

Journal of molecular and cellular cardiology - 1 Feb 1993

Mukherjee D, Sen S

Abstract excerpt

The myocardium contains a fibrillar collagen matrix that consists primarily of type I and type III collagens. There is a marked alteration in the ratio and amount of collagen phenotypes in myocardial hypertrophy due to pressure overload. The purpose of the present study is (1) to study the effect...

Topics

Animals
Blood Pressure
Captopril
Collagen
Hydralazine
Hypertension
Hypertrophy, Left Ventricular
Phenotype
Rats
Rats, Inbred SHR
Rats, Inbred WKY

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