Article
Analysis of linkage of the ACE locus with measures of cardiac hypertrophy in the spontaneously hypertensive rat.
Clinical and experimental pharmacology & physiology - 1 Jan 2000
Zhang L, Summers K M, West M J
Abstract excerpt
1. The effects of genetic factors on cardiac myocyte diameter and other phenotypes of heart size were determined in genetically hypertensive rats. Direct blood pressure, heartweight and cardiac myocyte size were measured at 12 weeks of age in spontaneously hypertensive rats (SHR) and normotensive...
Topics
- Animals
- Blood Pressure
- Cardiomegaly
- Cell Size
- Genetic Linkage
- Genotype
- Hypertension
- Male
- Muscle Fibers, Skeletal
- Myocardium
- Organ Size
- Peptidyl-Dipeptidase A
- Rats
- Rats, Inbred SHR
- Rats, Inbred WKY