Conditional expression and oncogenicity of c-myc linked to a CD2 gene dominant control region.

doi:10.1002/ijc.2910530628

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Article

Conditional expression and oncogenicity of c-myc linked to a CD2 gene dominant control region.

International journal of cancer - 1 Apr 1993

Stewart M, Cameron E, Campbell M, McFarlane R, Toth S, Lang K, Onions D, Neil J C

Abstract excerpt

Over-expression of the c-myc gene is widely implicated in the genesis of lymphoid neoplasia, including tumours of the T-cell lineage. To study the effects of deregulated c-myc expression on T-cell development and oncogenesis, we sought to generate a transgenic mouse model in which c-myc expressio...

Topics

Animals
Base Sequence
Female
Gene Expression
Gene Rearrangement
Gene Rearrangement, T-Lymphocyte
Genes, Dominant
Genes, Immunoglobulin
Genes, myc
Genetic Linkage
Humans
Leukemia, Experimental

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Leukemia, T-Cell

Lymphoma, T-Cell

Male

Mice

Mice, Inbred C57BL

Mice, Inbred CBA

Source

Open in PubMed

Identifiers

PMID: 8473043
DOI: 10.1002/ijc.2910530628

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8473043-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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