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Article

c-MYC: more than just a matter of life and death.

Nature reviews. Cancer - 1 Oct 2002

Pelengaris Stella, Khan Mike, Evan Gerard

Abstract excerpt

Deregulated expression of c-MYC occurs in a broad range of human cancers and is often associated with poor prognosis, indicating a key role for this oncogene in tumour progression. However, as established human tumours often bear multiple genetic lesions, it is difficult to determine whether c-MYC is instrumental in the initiation/progression of the tumour, or indeed whether inactivating c-MYC would lead to...

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Source

Identifiers

PMID: 12360279
DOI: 10.1038/nrc904

Genes

MYC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

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c-MYC—Making Liver Sick: Role of c-MYC in Hepatic Cell Function, Homeostasis and DiseaseSemantic proximity Read ↗

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