Article
Differential reactivity of TCR Vbeta10 alleles to a mouse mammary tumor virus superantigen.
European journal of immunology - 1 Oct 1998
Maillard I, Xenarios I, Diggelmann H, Orbea H A
Abstract excerpt
Mouse mammary tumor virus (MMTV) expresses a superantigen (SAg) which plays a critical role in the viral life cycle. We have recently described the new infectious MMTV (SIM) encoding a Vbeta4-specific SAg in mice with a TCR-Vbeta(b) haplotype. We have now compared the SAg activity of this virus in BALB/c mice harboring the TCR-Vbeta(a), TCR-Vbeta(b) or TCR-Vbeta(c) haplotypes which differ by a central deletion in...
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