Article
A Ca(2+)-independent protein kinase C from fission yeast.
The Journal of biological chemistry - 5 Apr 1993
Mazzei G J, Schmid E M, Knowles J K, Payton M A, Maundrell K G
Abstract excerpt
A protein kinase C homologue of Schizosaccharomyces pombe, pkc1+, was isolated from a genomic library by screening with the Saccharomyces cerevisiae PKC1 probe. From its primary sequence and biochemical properties, we conclude that S. pombe pkc1+ encodes a phospholipid-activated Ca(2+)-independent protein kinase, homologous to the delta/epsilon classes of mammalian protein kinase C. Gene disruption experiments...
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