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Article

Two novel protein kinase C-related genes of fission yeast are essential for cell viability and implicated in cell shape control.

The EMBO journal - 1 May 1993

Toda T, Shimanuki M, Yanagida M

Abstract excerpt

Two novel protein kinase C (PKC)-like genes, pck1+ and pck2+ were isolated from fission yeast by PCR. Both contain common domains of PKC-related molecules, but lack a putative Ca(2+)-binding domain so that they may belong to the nPKC group. Gene disruption of pck1+ and pck2+ establishes that they share an overlapping essential function for cell viability. Cells of a single pck2 deletion display severe defects in...

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Identifiers

PMID: 8491190
DOI: 10.1002/j.1460-2075.1993.tb05848.x
PMCID: PMC413420

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Source receipt: pubmed, retrieved 7 Sept 2026.

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