Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Mutants in the S. cerevisiae PKC1 gene display a cell cycle-specific osmotic stability defect.

The Journal of cell biology - 1 Mar 1992

Levin D E, Bartlett-Heubusch E

Abstract excerpt

The PKC1 gene of Saccharomyces cerevisiae encodes a homologue of the Ca(2+)-dependent isozymes of mammalian protein kinase C (Levin, D.cE., F. O. Fields, R. Kunisawa, J. M. Bishop, and J. Thorner. 1990. Cell. 62:213-224). Cells depleted of the PKC1 gene product display a uniform phenotype, a behavior indicating a defect in the cell division cycle (cdc). These cells arrest division after DNA replication, but...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles
Share to Amino Acid Sequence
Share to Cell Division

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Genes, Fungal

Share to Molecular Sequence Data

Share to Mutation

Share to Plasmids

Share to Saccharomyces cerevisiae

Source

Open in PubMed Open full text

Identifiers

PMID: 1740473
DOI: 10.1083/jcb.116.5.1221
PMCID: PMC2289351

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Mutants in the S. cerevisiae PKC1 gene display a cell cycle-specific osmotic stability defect.PMID 1740473Read ↗

Dissecting the protein kinase C/MAP kinase signalling pathway of Saccharomyces cerevisiae.Semantic proximity Read ↗

Implication of Pkc1p protein kinase C in sustaining Cln2p level and polarized bud growth in response to calcium signaling in Saccharomyces cerevisiae.Semantic proximity Read ↗

The osmotic integrity of the yeast cell requires a functional PKC1 gene product.Semantic proximity Read ↗

Mutation of the gene encoding protein kinase C 1 stimulates mitotic recombination in Saccharomyces cerevisiae.Semantic proximity Read ↗

Calcineurin, the Ca2+/calmodulin-dependent protein phosphatase, is essential in yeast mutants with cell integrity defects and in mutants that lack a functional vacuolar H(+)-ATPase.Semantic proximity Read ↗

BRO1, a novel gene that interacts with components of the Pkc1p-mitogen-activated protein kinase pathway in Saccharomyces cerevisiae.Semantic proximity Read ↗

Saccharomyces cerevisiae PKC1 encodes a protein kinase C (PKC) homolog with a substrate specificity similar to that of mammalian PKC.Semantic proximity Read ↗

Cdc1p is an endoplasmic reticulum-localized putative lipid phosphatase that affects Golgi inheritance and actin polarization by activating Ca2+ signaling.Semantic proximity Read ↗

The protein kinase C-activated MAP kinase pathway of Saccharomyces cerevisiae mediates a novel aspect of the heat shock response.Semantic proximity Read ↗

Cks1 is dispensable for survival in Saccharomyces cerevisiae.Semantic proximity Read ↗

Isolation and characterization of temperature-sensitive plc1 mutants of the yeast Saccharomyces cerevisiae.Semantic proximity Read ↗

The Cak1p protein kinase is required at G1/S and G2/M in the budding yeast cell cycle.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.