Article
Evolution, biochemistry and genetics of protein kinase C in fungi.
Current genetics - 1 Jul 2003
Schmitz Hans-Peter, Heinisch Jürgen J
Abstract excerpt
From yeast to humans, protein kinase C is an enzyme of central importance in signal transduction processes. In baker's yeast, Saccharomyces cerevisiae, a single gene encoding Pkc1p has been identified. Mutant analyses revealed that Pkc1p function is essential to ensure cellular integrity through regulation of a specific MAP kinase cascade. Due to the involvement of different defective mammalian isozymes in...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
