Article
Crystal structures of two mutants of adenylate kinase from Escherichia coli that modify the Gly-loop.
Proteins - 1 Jan 1993
Müller C W, Schulz G E
Abstract excerpt
Two mutants of adenylate kinase from Escherichia coli have been crystallized and analyzed by X-ray diffraction at resolutions of 3.4 and 2.4 A, respectively. These mutants are Pro-9-->Leu and Gly-10-->Val. They were selected for their positions in the highly conserved Gly-loop forming a giant anion hole for the beta-phosphate of ATP (GTP) in adenylate kinases, H-ras-p21, and other nucleotide-binding proteins....
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