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Article

cis-dominant regulation of CD4 and CD8 gene expression in rat/mouse T cell heterohybridomas.

Journal of immunology (Baltimore, Md. : 1950) - 15 Mar 1993

Gocinski B L, Sun D, Coleclough C

Abstract excerpt

To determine whether expression of CD4 and CD8 molecules on T cells is determined-solely by transacting regulators, we examined heterohybridomas derived from the fusion of a rat CD4+ T cell line and the CD4- CD8- mouse thymoma BW5147. The majority of hybrid offspring expressed rat CD4. However, a...

Topics

Animals
CD4 Antigens
CD8 Antigens
Cell Fusion
Cell Separation
Clone Cells
DNA
Female
Gene Expression Regulation
Hybridomas
Methylation
Mice
Mice, Inbred BALB C

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Phenotype

Rats

Rats, Inbred Lew

Regulatory Sequences, Nucleic Acid

Species Specificity

Source

Identifiers

PMID: 8450209

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8450209-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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