Article
The investigation of allele and genotype frequencies of human C3 (rs2230199) in south Iranian population.
Molecular biology reports - 1 Sept 2012
Bazyar Najmeh, Azarpira Negar, Khatami Saied Reza, Galehdari Hamid
Abstract excerpt
The complement system is an important mediator of natural and acquired immunity. The complement system genes coding complement proteins have polymorphisms. Hereditary deficiencies of this system predispose to autoimmune conditions such as age-dependent macular degeneration or impairment of immunity against microorganisms. When different populations are compared, the frequency of complement polymorphism shows a...
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