Bone marrow clones representing an intermediate stage of development between hematopoietic stem cells and pro-T-lymphocyte or pro-B-lymphocyte progenitors.

Abstract excerpt

We have established in culture several nontransformed bone marrow clones (called PR) that show phenotypic and genotypic characteristics that distinguish them from totipotent stem cells and lineage-restricted Pro-T lymphocytes, Pro-B lymphocytes, and myeloid cell progenitors. In vivo and/or in vit...

Topics

• Animals
• B-Lymphocytes
• Base Sequence
• Bone Marrow Cells
• Cell Differentiation
• Clone Cells
• Female
• Gene Expression
• Growth Substances
• Hematopoietic Stem Cells
• Mice
• Mice, Inbred CBA
• Molecular Sequence Data
• Phenotype
• Receptors, Antigen, T-Cell, alpha-beta
• Receptors, Antigen, T-Cell, gamma-delta
• T-Lymphocytes