Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Clonal analysis of hematopoietic stem-cell differentiation in vivo.

1 Apr 1991

Abstract excerpt

Previous work has shown that the 0.02-0.05% of adult mouse bone marrow cells that bear the cell surface phenotype Thy-1loLin-Sca-1+ are enriched 1000- to 2000-fold for hematopoietic stem-cell activity in a variety of assays. When 50-100 cells of this phenotype are injected into an irradiated animal, they can permanently repopulate the entire hematopoietic system. In the present study, limiting-dilution and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Cells and Metastasis
Share to Cancer Genomics and Diagnostics
Share to Single-cell and spatial transcriptomics

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 1672767
DOI: 10.1073/pnas.88.7.2788

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Clonal analysis of hematopoietic stem-cell differentiation in vivo.PMID 1672767Read ↗

Searching for hematopoietic stem cells: evidence that Thy-1.1lo Lin- Sca-1+ cells are the only stem cells in C57BL/Ka-Thy-1.1 bone marrow.Semantic proximity Read ↗

The hematopoietic stem compartment consists of a limited number of discrete stem cell subsetsSemantic proximity Read ↗

In Vivo Tracking of Human Hematopoiesis Reveals Patterns of Clonal Dynamics during Early and Steady-State Reconstitution PhasesSemantic proximity Read ↗

Phenotypic and functional characterization of the hematopoietic stem cell.Semantic proximity Read ↗

Life span of multipotential hematopoietic stem cells in vivo.Semantic proximity Read ↗

Predicting clonal self-renewal and extinction of hematopoietic stem cellsSemantic proximity Read ↗

Clonal diversity of the stem cell compartmentSemantic proximity Read ↗

Large-Scale Clonal Analysis Resolves Aging of the Mouse Hematopoietic Stem Cell CompartmentSemantic proximity Read ↗

Bone marrow clones representing an intermediate stage of development between hematopoietic stem cells and pro-T-lymphocyte or pro-B-lymphocyte progenitors.Semantic proximity Read ↗

Culture of phenotypically defined hematopoietic stem cells and other progenitors at limiting dilution on Dexter monolayers.Semantic proximity Read ↗

A new mechanism for the aging of hematopoietic stem cells: aging changes the clonal composition of the stem cell compartment but not individual stem cellsSemantic proximity Read ↗

Functional compensation between hematopoietic stem cell clones in vivo.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.