Article
Identification and genetic mapping of CHL genes controlling mitotic chromosome transmission in yeast.
Yeast (Chichester, England) - 1 Jan 1993
Kouprina N, Tsouladze A, Koryabin M, Hieter P, Spencer F, Larionov V
Abstract excerpt
Eight independent chl (chromosome loss) mutants were isolated using yeast haploid strain disomic for chromosome III. In these mutants, chromosome III is lost during mitosis 50-fold more frequently than in the wild-type strains. chl mutants are also incapable of stable maintenance of circular and linear artificial chromosomes. Seven of the eight mutations are recessive, and one is semidominant. Complementation...
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