Article
Epstein-Barr virus latent membrane protein 2A preferentially signals through the Src family kinase Lyn.
Journal of virology - 1 Sept 2008
Rovedo Mark, Longnecker Richard
Abstract excerpt
Latent membrane protein 2A (LMP2A) is a viral protein expressed during Epstein-Barr virus (EBV) latency in EBV-infected B cells both in cell culture and in vivo. LMP2A has important roles in modulating B-cell receptor signal transduction and provides survival and developmental signals to B cells in vivo. Although Lyn has been shown to be important in mediating LMP2A signaling, it is still unclear if Lyn is used...
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