Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Morphogenic capabilities of human immunodeficiency virus type 1 gag and gag-pol proteins in insect cells.

Virology - 1 Mar 1993

Hughes B P, Booth T F, Belyaev A S, McIlroy D, Jowett J, Roy P

Abstract excerpt

To determine the interaction between the gag precursor and the viral protease and to confirm the role of gag precursor in formation of human immunodeficiency virus type 1 particles, the gag and protease encoding regions of a proviral genome with mutations at the site between p17 and p24 or p24 and p15 were expressed by recombinant baculoviruses under the transcriptional control of the strong polyhedrin promoter....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amino Acid Sequence
Share to Gene Products, gag
Share to HIV-1

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Molecular Sequence Data

Share to Morphogenesis

Share to Mutation

Share to Recombinant Proteins

Source

Identifiers

PMID: 8438569
DOI: 10.1006/viro.1993.1120

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Morphogenic capabilities of human immunodeficiency virus type 1 gag and gag-pol proteins in insect cells.PMID 8438569Read ↗

Morphopoietic determinants of HIV-1 Gag particles assembled in baculovirus-infected cells.Semantic proximity Read ↗

Role of the C terminus Gag protein in human immunodeficiency virus type 1 virion assembly and maturation.Semantic proximity Read ↗

p6Gag is required for particle production from full-length human immunodeficiency virus type 1 molecular clones expressing proteaseSemantic proximity Read ↗

Proteolytic activity of novel human immunodeficiency virus type 1 proteinase proteins from a precursor with a blocking mutation at the N terminus of the PR domain.Semantic proximity Read ↗

Overexpression of the gag-pol precursor from human immunodeficiency virus type 1 proviral genomes results in efficient proteolytic processing in the absence of virion productionSemantic proximity Read ↗

Maintenance of the Gag/Gag-Pol Ratio Is Important for Human Immunodeficiency Virus Type 1 RNA Dimerization and Viral InfectivitySemantic proximity Read ↗

Extensive regions of pol are required for efficient human immunodeficiency virus polyprotein processing and particle maturation.Semantic proximity Read ↗

Cotransfection of mutated forms of human immunodeficiency virus type 1 Gag-Pol with wild-type constructs can interfere with processing and viral replication.Semantic proximity Read ↗

Characterization of human immunodeficiency virus type-1 (HIV-1) particles that express protease-reverse transcriptase fusion proteins.Semantic proximity Read ↗

Effects of human immunodeficiency virus type 1 transframe protein p6* mutations on viral protease-mediated Gag processing.Semantic proximity Read ↗

Reverse transcriptase and protease activities of avian leukosis virus Gag-Pol fusion proteins expressed in insect cells.Semantic proximity Read ↗

Characterization of deletion mutations in the capsid region of human immunodeficiency virus type 1 that affect particle formation and Gag-Pol precursor incorporationSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.