Article
Autologous antibody response against the principal neutralizing domain of human immunodeficiency virus type 1 isolated from infected humans.
Journal of virology - 1 Mar 1993
Holmbäck K, Kusk P, Hulgaard E F, Bugge T H, Scheibel E, Lindhardt B O
Abstract excerpt
High titers of neutralizing antibodies in human immunodeficiency virus type 1 (HIV-1) infection are directed primarily against the third hypervariable domain (V3) of the virion envelope glycoprotein gp120. This region has been designated the principal neutralizing domain of HIV-1. Because the fre...
Topics
- Amino Acid Sequence
- Antibodies, Heterophile
- Base Sequence
- Cloning, Molecular
- Cross Reactions
- Genetic Variation
- HIV Antibodies
- HIV Envelope Protein gp120
- HIV Infections
- HIV-1
- Hemophilia A
- Humans
- Molecular Sequence Data
- Oligodeoxyribonucleotides
- Polymerase Chain Reaction