Article
Diversity of antibody binding to V3 peptides representing consensus sequences of HIV type 1 genotypes A to E: an approach for HIV type 1 serological subtyping.
AIDS research and human retroviruses - 1 Sept 1996
Barin F, Lahbabi Y, Buzelay L, Lejeune B, Baillou-Beaufils A, Denis F, Mathiot C, M'Boup S, Vithayasai V, Dietrich U, Goudeau A
Abstract excerpt
We investigated whether V3-binding assays might be useful to analyze human immunodeficiency virus type 1 (HIV-1) variants in different geographic regions. We showed that strong cross-reactivity between subtype-specific V3 peptides is almost inevitable in standard indirect enzyme-linked immunosorb...
Topics
- Amino Acid Sequence
- Antibody Diversity
- Binding Sites, Antibody
- Cluster Analysis
- Consensus Sequence
- Genotype
- HIV Antibodies
- HIV Envelope Protein gp120
- HIV Infections
- HIV-1
- Humans
- Immunoenzyme Techniques
- Longitudinal Studies