Molecular characterization of human monoclonal antibodies specific for several HIV proteins: analysis of the VH3 family expression.

doi:10.1016/0165-2478(95)00078-j

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Article

Molecular characterization of human monoclonal antibodies specific for several HIV proteins: analysis of the VH3 family expression.

Immunology letters - 1 Jan 2000

David D, Goossens D, Desgranges C, Thèze J, Zouali M

Abstract excerpt

We have analyzed the heavy-chain variable (VH) region genes expressed by a panel of human monoclonal antibodies derived from an immunized volunteer, an AIDS patient and seropositive asymptomatic donors, and specific for HIV-1 env, pol and gag gene products. The third complementarity-determining r...

Topics

Antibodies, Monoclonal
Antibody Specificity
Base Sequence
Gene Products, env
Gene Products, gag
Gene Products, pol
HIV Antigens
Humans
Immunoglobulin Heavy Chains
Immunoglobulin Variable Region
Molecular Sequence Data
Multigene Family
Mutation

Source

Open in PubMed

Identifiers

PMID: 8537086
DOI: 10.1016/0165-2478(95)00078-j

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8537086-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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