Article
V3 seroreactivity and sequence variation: tracking the emergence of V3 genotypic variation in HIV-1-infected patients.
AIDS (London, England) - 1 Feb 1996
Michael N L, Davis K E, Loomis-Price L D, VanCott T C, Burke D S, Redfield R R, Birx D L
Abstract excerpt
OBJECTIVE: To investigate the relationship between V3-specific immune responses and viral quasispecies evolution in 10 HIV-1-seropositive patients enrolled in a phase I trial of recombinant gp160. METHODS: Serologic responses to the HIVLAI V3 loop and autologous V3 loop DNA sequences were sequent...
Topics
- AIDS Vaccines
- Adult
- Amino Acid Sequence
- Carrier Proteins
- Cohort Studies
- Evolution, Molecular
- Genes, env
- Genetic Variation
- HIV Antibodies
- HIV Envelope Protein gp120
- HIV Envelope Protein gp160
