Article
Antibodies of symptomatic human immunodeficiency virus type 1-infected individuals are directed to the V3 domain of noninfectious and not of infectious virions present in autologous serum.
Journal of virology - 1 Jun 1994
Schreiber M, Petersen H, Wachsmuth C, Müller H, Hufert F T, Schmitz H
Abstract excerpt
The present study was designed to determine the antibody specificity for the human immunodeficiency virus type 1 (HIV-1) V3 domains of infectious and noninfectious virions present in the serum of AIDS patients. To accomplish this, HIV-1 was isolated in the presence of autologous antibodies from the serum samples of six AIDS patients in HIV-1-negative donor peripheral blood mononuclear cells by short-term...
Topics
- Acquired Immunodeficiency Syndrome
- Amino Acid Sequence
- Antibody Specificity
- Base Sequence
- DNA, Viral
- Genes, env
- Genetic Variation
- Glutathione Transferase
- HIV Antibodies
- HIV Antigens